Uganda has taken a historic step in the fight against malaria as the Minister of Health, Hon. Dr. Jane Ruth Aceng Ocero, officially flagged off the distribution of 2.278 million doses of malaria vaccines to 105 districts with high and moderate transmission rates.
This marks the largest malaria vaccine introduction in the country’s history, with the rollout expected to expand nationwide.
The initiative is supported by Gavi, the Vaccine Alliance, with co-financing from the Government of Uganda. UNICEF has played a key role in procuring and transporting the vaccines to ensure timely distribution.

The malaria vaccine will be incorporated into Uganda’s routine immunization programme starting in April 2025, targeting children under two years old.
“This is a historic step forward in our fight against malaria,” Dr. Aceng stated at the flag-off event. “With the support of Gavi, UNICEF, and other partners, we are ensuring that every eligible child has access to this life-saving intervention.”
The vaccine will be administered in four doses at 6, 7, 8, and 18 months to provide optimal protection. Malaria remains a leading cause of illness and death among young children in Uganda, and this vaccine is expected to significantly reduce severe cases and fatalities.
Dr. Robin Nandy, UNICEF Representative to Uganda, emphasized the importance of the rollout: “With the introduction of the malaria vaccine, we are delivering hope for children in Uganda. This milestone strengthens the national immunization schedule, which now includes 14 vaccines.”

Gavi, which coordinates global malaria vaccine programmes, has supported 17 African nations in introducing the vaccine. Billie Nieuwenhuys, Senior Country Manager for Uganda at Gavi, praised the country’s efforts: “This rollout is a testament to Uganda’s commitment to protecting vulnerable children. We look forward to seeing the impact of this programme in reducing the burden of malaria.”
The World Health Organization (WHO) has played a crucial role in evaluating the vaccine and supporting its integration into immunization schedules. Uganda’s Ministry of Health has also reaffirmed its commitment to a comprehensive malaria prevention strategy, which includes insecticide-treated nets, indoor residual spraying, seasonal malaria chemoprevention, and effective case management.
The Ministry urges parents and caregivers to ensure their children receive the vaccine as part of routine immunization services. The rollout aligns Uganda with other African nations making strides in malaria prevention, with more countries expected to introduce the vaccine in 2025.
